Dome C site testing: surface layer, free atmosphere seeing and isoplanatic angle statistics

This paper analyses 3.5 years of site testing data obtained at Dome C, Antarctica, based on measurements obtained with three DIMMs located at three different elevations. Basic statistics of the seeing and the isoplanatic angle are given, as well as the characteristic time of temporal fluctuations of these two parameters, which we found to around 30 minutes at 8 m. The 3 DIMMs are exploited as a profiler of the surface layer, and provide a robust estimation of its statistical properties. It appears to have a very sharp upper limit (less than 1 m). The fraction of time spent by each telescope above the top of the surface layer permits us to deduce a median height of between 23 m and 27 m. The comparison of the different data sets led us to infer the statistical properties of the free atmosphere seeing, with a median value of 0.36 arcsec. The C_n^2 profile inside the surface layer is also deduced from the seeing data obtained during the fraction of time spent by the 3 telescopes inside this turbulence. Statistically, the surface layer, except during the 3-month summer season, contributes to 95 percent of the total turbulence from the surface level, thus confirming the exceptional quality of the site above it

CoRoT light curves of RR Lyrae stars. CoRoT 101128793: long-term changes in the Blazhko effect and excitation of additional modes

The CoRoT (Convection, Rotation and planetary Transits) space mission provides a valuable opportunity to monitor stars with uninterrupted time sampling for up to 150 days at a time. The study of RR Lyrae stars, performed in the framework of the Additional Programmes belonging to the exoplanetary field, will particularly benefit from such dense, long-duration monitoring. The Blazhko effect in RR Lyrae stars is a long-standing, unsolved problem of stellar astrophysics. We used the CoRoT data of the new RR Lyrae variable CoRoT 101128793 (f0=2.119 c/d, P=0.4719296 d) to provide us with more detailed observational facts to understand the physical process behind the phenomenon. The CoRoT data were corrected for one jump and the long-term drift. We applied different period-finding techniques to the corrected timeseries to investigate amplitude and phase modulation. We detected 79 frequencies in the light curve of CoRoT 101128793. They have been identified as the main frequency f0, and its harmonics, two independent terms, the terms related to the Blazhko frequency, and several combination terms. A Blazhko frequency fB=0.056 c/d and a triplet structure around the fundamental radial mode and harmonics were detected, as well as a long-term variability of the Blazhko modulation. Indeed, the amplitude of the main oscillation is decreasing along the CoRoT survey. The Blazhko modulation is one of the smallest observed in RR Lyrae stars. Moreover, the additional modes f1=3.630 and f2=3.159 c/d are detected. Taking its ratio with the fundamental radial mode into account, the term f1 could be the identified as the second radial overtone. Detecting of these modes in horizontal branch stars is a new result obtained by CoRoT.Comment: 13 pages, 2 figures, 2 long tables. Accepted for publication in A&

ASTEP South: An Antarctic Search for Transiting ExoPlanets around the celestial South pole

ASTEP South is the first phase of the ASTEP project (Antarctic Search for Transiting ExoPlanets). The instrument is a fixed 10 cm refractor with a 4kx4k CCD camera in a thermalized box, pointing continuously a 3.88 degree x 3.88 degree field of view centered on the celestial South pole. ASTEP South became fully functional in June 2008 and obtained 1592 hours of data during the 2008 Antarctic winter. The data are of good quality but the analysis has to account for changes in the point spread function due to rapid ground seeing variations and instrumental effects. The pointing direction is stable within 10 arcseconds on a daily timescale and drifts by only 34 arcseconds in 50 days. A truly continuous photometry of bright stars is possible in June (the noon sky background peaks at a magnitude R=15 arcsec-2 on June 22), but becomes challenging in July (the noon sky background magnitude is R=12.5 arcsec?2 on July 20). The weather conditions are estimated from the number of stars detected in the field. For the 2008 winter, the statistics are between 56.3 % and 68.4 % of excellent weather, 17.9 % to 30 % of veiled weather and 13.7 % of bad weather. Using these results in a probabilistic analysis of transit detection, we show that the detection efficiency of transiting exoplanets in one given field is improved at Dome C compared to a temperate site such as La Silla. For example we estimate that a year-long campaign of 10 cm refractor could reach an efficiency of 69 % at Dome C versus 45 % at La Silla for detecting 2-day period giant planets around target stars from magnitude 10 to 15. This shows the high potential of Dome C for photometry and future planet discoveries. [Short abstract

Sprouty2 mediated tuning of signalling is essential for somite myogenesis

Background: Negative regulators of signal transduction cascades play critical roles in controlling different aspects of normal embryonic development. Sprouty2 (Spry2) negatively regulates receptor tyrosine kinases (RTK) and FGF signalling and is important in differentiation, cell migration and proliferation. In vertebrate embryos, Spry2 is expressed in paraxial mesoderm and in forming somites. Expression is maintained in the myotome until late stages of somite differentiation. However, its role and mode of action during somite myogenesis is still unclear. Results: Here, we analysed chick Spry2 expression and showed that it overlaps with that of myogenic regulatory factors MyoD and Mgn. Targeted mis-expression of Spry2 led to inhibition of myogenesis, whilst its C-terminal domain led to an increased number of myogenic cells by stimulating cell proliferation. Conclusions: Spry2 is expressed in somite myotomes and its expression overlaps with myogenic regulatory factors. Overexpression and dominant-negative interference showed that Spry2 plays a crucial role in regulating chick myogenesis by fine tuning of FGF signaling through a negative feedback loop. We also propose that mir-23, mir-27 and mir-128 could be part of the negative feedback loop mechanism. Our analysis is the first to shed some light on in vivo Spry2 function during chick somite myogenesis

Large-Scale Clonal Analysis Reveals Unexpected Complexity in Surface Ectoderm Morphogenesis

Background: Understanding the series of morphogenetic processes that underlie the making of embryo structures is a highly topical issue in developmental biology, essential for interpreting the massive molecular data currently available. In mouse embryo, long-term in vivo analysis of cell behaviours and movements is difficult because of the development in utero and the impossibility of long-term culture. Methodology/Principal Findings: We improved and combined two genetic methods of clonal analysis that together make practicable large-scale production of labelled clones. Using these methods we performed a clonal analysis of surface ectoderm (SE), a poorly understood structure, for a period that includes gastrulation and the establishment of the body plan. We show that SE formation starts with the definition at early gastrulation of a pool of founder cells that is already dorso-ventrally organized. This pool is then regionalized antero-posteriorly into three pools giving rise to head, trunk and tail. Each pool uses its own combination of cell rearrangements and mode of proliferation for elongation, despite a common clonal strategy that consists in disposing along the antero-posterior axis precursors of dorso-ventrally-oriented stripes of cells. Conclusions/Significance: We propose that these series of morphogenetic processes are organized temporally and spatially in a posterior zone of the embryo crucial for elongation. The variety of cell behaviours used by SE precursor cells indicates that these precursors are not equivalent, regardless of a common clonal origin and a common clonal strategy. Anothe

α5β1 Integrin-Mediated Adhesion to Fibronectin Is Required for Axis Elongation and Somitogenesis in Mice

The arginine-glycine-aspartate (RGD) motif in fibronectin (FN) represents the major binding site for α5β1 and αvβ3 integrins. Mice lacking a functional RGD motif in FN (FNRGE/RGE) or α5 integrin develop identical phenotypes characterized by embryonic lethality and a severely shortened posterior trunk with kinked neural tubes. Here we show that the FNRGE/RGE embryos arrest both segmentation and axis elongation. The arrest is evident at about E9.0, corresponding to a stage when gastrulation ceases and the tail bud-derived presomitic mesoderm (PSM) induces α5 integrin expression and assumes axis elongation. At this stage cells of the posterior part of the PSM in wild type embryos are tightly coordinated, express somitic oscillator and cyclic genes required for segmentation, and form a tapered tail bud that extends caudally. In contrast, the posterior PSM cells in FNRGE/RGE embryos lost their tight associations, formed a blunt tail bud unable to extend the body axis, failed to induce the synchronised expression of Notch1 and cyclic genes and cease the formation of new somites. Mechanistically, the interaction of PSM cells with the RGD motif of FN is required for dynamic formation of lamellipodia allowing motility and cell-cell contact formation, as these processes fail when wild type PSM cells are seeded into a FN matrix derived from FNRGE/RGE fibroblasts. Thus, α5β1-mediated adhesion to FN in the PSM regulates the dynamics of membrane protrusions and cell-to-cell communication essential for elongation and segmentation of the body axis

Low loss coatings for the VIRGO large mirrors

présentée par L. PinardThe goal of the VIRGO program is to build a giant Michelson type interferometer (3 kilometer long arms) to detect gravitational waves. Large optical components (350 mm in diameter), having extremely low loss at 1064 nm, are needed. Today, the Ion beam Sputtering is the only deposition technique able to produce optical components with such performances. Consequently, a large ion beam sputtering deposition system was built to coat large optics up to 700 mm in diameter. The performances of this coater are described in term of layer uniformity on large scale and optical losses (absorption and scattering characterization). The VIRGO interferometer needs six main mirrors. The first set was ready in June 2002 and its installation is in progress on the VIRGO site (Italy). The optical performances of this first set are discussed. The requirements at 1064 nm are all satisfied. Indeed, the absorption level is close to 1 ppm (part per million), the scattering is lower than 5 ppm and the R.M.S. wavefront of these optics is lower than 8 nm on 150 mm in diameter. Finally, some solutions are proposed to further improve these performances, especially the absorption level (lower than 0.1 ppm) and the mechanical quality factor Q of the mirrors (thermal noise reduction)

The gravitational wave detector VIRGO

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The Virgo data acquisition system

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Search for non-Gaussian events in the data of the VIRGO E4 engineering run

International audienc